Grease stains are one of the toughest laundry problems, often clinging to clothes even after a normal wash. From cooking oil splashes to motor grease and food spills, these stains can quickly ruin your favorite outfits if not treated properly.
That is why choosing the right grease stain remover is essential for keeping your clothes fresh, clean, and long lasting. With so many products available, finding the most effective option can feel overwhelming.
This guide highlights the top 10 best grease stain removers for clothes, carefully selected for their cleaning power, fabric safety, and ease of use, helping you restore stained garments with confidence.
10. Grandma’s Secret 2 Ounce Stain Remover
Grandma’s Secret Spot Remover is the gentle powerhouse you’ve been waiting for. Its toxin‑free formula attacks stubborn stains—oil, paint, blood, pet accidents, rust, and even baby diaper leaks—without stripping color or leaving a chalky residue.
Because it contains no bleach, chlorine, or phosphates, you can trust it on delicate fabrics, heirloom pieces, and everyday wear alike. A pleasant citrus scent follows each application, turning stain‑fighting into a fresh experience.
The concentrated 2‑ounce bottle works in any water temperature, so you can treat fresh spills or set‑in marks straight from the washing machine.
Simply dab, agitate, and blot; the stain disappears, leaving the fabric as vibrant as before. Ideal for families, pet owners, and anyone who values a safe, effective cleaning solution that respects both clothing and skin.
Pros
- Removes stains without fading colors
- No bleach, chlorine, or phosphates
- Works on fresh and set‑in stains
- Safe for baby clothes and skin
- Leaves a fresh citrus fragrance
Cons
- Small 2‑ounce size may need frequent refills
- Requires immediate application for best results
- Not a substitute for heavy‑duty industrial cleaners
9. OxiClean Max Force Laundry Stain Remover Spray, 3-Pack
OxiClean Max Force Laundry Stain Remover Spray is a newborn‑and‑baby essential that tackles set‑in stains the first time you treat them.
The 12 fl oz bottles come in a convenient 3‑pack, so you can spray on a fresh mess and still have up to 7 days before the next wash.
Its 5‑in‑1 stain‑fighter blend penetrates tough spots—from berry juice and baby food to grass, mud, oil, coffee, wine, chocolate, ketchup, blood, ink, and washable paint—while staying color‑safe and gentle on fabrics.
The enzymatic formula contains no chlorine bleach, brighteners, dyes, or phosphates, making it safe for delicate baby clothes and a wide range of machine‑washable fabrics such as cotton, linen, spandex, fleece, polyester, nylon, denim, canvas shoes, and even workout gear.
Whether you’re rescuing a tiny onesie or a family‑sized sheet set, OxiClean Max Force delivers powerful stain removal without compromising softness or color integrity.
Pros
- Removes set‑in stains on first application
- Spray now, wash up to seven days later
- Color‑safe, enzymatic, no harsh chemicals
- Works on all machine‑washable fabrics
- 5‑in‑1 formula tackles food, grass, oil, ink
Cons
- Requires a full day before washing for best results
- Spray may feel wet on delicate fabrics initially
- Pack size may be bulky for travel kits
8. OxiClean Max Force Stain Remover
Tackle the toughest, dried‑in stains without breaking a sweat. The compact gel stick delivers a concentrated dose of OxiClean’s proven oxygen‑based cleaning power, letting you pretreat a spot now and wash it up to seven days later—perfect for busy families or last‑minute laundry emergencies.
Its thick, rub‑on formula saturates quickly, working through oil, grease, makeup, blood, grass, soil, clay, ink, food, drinks, and even the most stubborn kid‑or‑baby messes.
Because the gel is color‑safe, dye‑free, and chlorine‑free, you can confidently use it on any machine‑washable white or colored fabric, including delicate baby clothes.
After a five‑minute (or up to seven‑day) dwell time, simply toss the garment into the warmest water safe for the fabric and wash as usual. For an extra boost, add OxiClean Versatile Stain Remover powder to the wash following the label directions.
Pros
- Pretreat now, wash up to seven days later
- Handles oil, grease, makeup, and blood stains
- Safe for all colors, dyes, and baby fabrics
- No chlorine, dye, or harsh chemicals present
- Compact stick fits easily in laundry rooms
Cons
- Gel may feel sticky on hands
- Requires warm water for optimal results
- Not a substitute for heavy‑duty carpet cleaners
7. Miss Mouth’s Messy Eater Stain Treater Spray – 16oz
Miss Mouth’s Messy Eater Stain Treater Spray is the go‑to rescue for every diaper change, snack‑time spill, or coffee mishap. This 16 oz lightning‑fast formula attacks food, grease, blood, and even set‑in marks on baby clothes, upholstery, carpets, and underwear.
Simply dab away excess mess, spray the spot, give a quick rub, and toss the item into the wash—repeat if needed for stubborn spots.
The EPA Safer Choice certification means the ingredients are rigorously vetted for health and environmental safety, so you can treat stains without worrying about harsh chemicals.
Whether you’re dealing with newborn formula dribbles or a toddler’s ketchup explosion, Miss Mouth’s delivers a powerful clean that’s gentle enough for the whole family.
Pros
- Lightning‑fast action removes stains instantly
- EPA Safer Choice certified for peace of mind
- Works on fresh and set‑in stains alike
- Safe for baby clothes, upholstery, and carpets
- Simple spray‑rub‑wash routine, no extra steps
Cons
- Requires a brief pre‑wetting step
- May need a second spray for deep set stains
- Not intended for delicate silk or leather fabrics
6. Puracy Stain Remover (12 fl oz)
Puracy Stain Remover spray is a gentle‑yet‑mighty solution for everyday messes and stubborn set‑in spots.
The plant‑ and mineral‑based formula works quickly on fresh spills while still breaking down older stains, so you can rescue favorite shirts, baby blankets, or upholstered furniture in seconds.
Its unscented, non‑bleach composition tackles a wide range of culprits—grass, red wine, makeup, oil, and even lingering odors—without compromising fabric integrity.
Safe for delicate linens, active‑wear, and pet‑friendly upholstery, the spray is free of sulfates, parabens, bleaches, and petrochemicals, making it a worry‑free addition to any household.
Just spray, wait a moment, and launder as usual for a fresh, spotless finish. The 12 fl oz bottle is travel‑ready, so you’re always prepared for unexpected spills on the go.
Pros
- Powerful stain removal without harsh chemicals
- Unscented formula keeps clothes odor‑free
- Safe on all fabric types, including delicates
- Free from sulfates, parabens, and bleaches
- Travel‑size convenience for on‑the‑spot cleaning
Cons
- Requires a short dwell time for best results
- Not ideal for extremely large, heavily set stains
- May need a second application on tough oil spots
5. Grandma’s Secret Spot Remover Laundry Spray
Grandma’s Secret Spot Remover Laundry Spray is the go‑to solution for anyone who refuses to let stubborn stains ruin their favorite garments.
Formulated without chlorine, bleach, or harsh phosphates, this toxin‑free spray attacks oil, paint, blood, pet accidents, and even rust without stripping color or leaving a gritty residue.
A pleasant citrus scent follows each application, turning stain‑fighting into a fresh experience. The concentrated formula works in any water temperature, so you can treat a fresh spill or a set‑in mark that survived a previous wash.
Perfect for baby‑related messes, it lifts diaper leaks, puree splatters, and other “little‑one” mishaps without harming delicate fabrics. Application is simple: spray, gently agitate, then blot—no scrubbing, no special equipment.
The DuoPack includes a 16 oz bottle for everyday use and a handy 2 oz travel size, ensuring you’re always prepared, whether at home or on the go.
Pros
- Harsh on stains, gentle on fabrics
- No bleach, chlorine, or phosphates
- Works on a wide variety of stains
- Pleasant citrus fragrance after use
- Easy three‑step application process
Cons
- Strong scent may not suit all preferences
- Requires blotting, not a rinse‑only solution
- May need repeat application on very old stains
4. Miss Mouth’s Messy Eater Stain Treater
Miss Mouth’s Messy Eater Stain Treater Spray is the go‑to rescue for every little (and not‑so‑little) spill that threatens your baby’s wardrobe, upholstery, or carpet.
This 4 oz lightning‑fast formula attacks food, grease, coffee, blood and even set‑in stains, turning a nightmare into a quick rinse‑and‑wash.
The spray is EPA Safer Choice certified, so you can trust it’s gentle on skin and the environment while still delivering powerhouse cleaning power.
Using it is a breeze: dab away excess mess, dampen the spot with a splash of water, spray Miss Mouth’s, give a gentle rub if needed, then toss the item into the wash. If the stain persists, repeat—no hassle, no harsh chemicals.
Perfect for newborns, toddlers, and the whole family, it works on everything from fruit juice to ketchup blowouts, keeping clothes, underwear, and fabrics looking fresh without a trip to the dry cleaners.
Pros
- Lightning‑fast action on fresh and set‑in stains
- EPA Safer Choice certified for family safety
- Works on fabrics, upholstery, and carpets alike
- Simple three‑step application, no rinsing required
- Effective on food, grease, coffee, and blood
Cons
- Small 4 oz size may need frequent refills
- Not ideal for extremely large, deep‑set stains
- Requires a brief wait before washing for best results
3. Shout Advanced Scrub Gel
Shout Advanced Stain Remover Gel is a super‑concentrated, thick gel that tackles the toughest set‑in stains—think red wine, grass, blood, makeup, and more.
The 8.7 oz bottle comes with a built‑in scrubber brush, letting you work the enzyme‑rich formula deep into fabric fibers without needing an extra tool.
Its ultra‑concentrated formula means a little goes a long way, and it’s safe for both whites and colors, HE or standard washers, and any water temperature.
Simply squeeze the gel onto the stain, use the brush to work it in, and toss the garment into the wash; you can even treat the spot and wash up to a week later. The gel is tough on grime yet gentle on fibers, making it a reliable staple for any laundry room.
Pros
- Built‑in brush eliminates extra cleaning tools
- Ultra‑concentrated gel saves money per load
- Works on all fabrics, whites, and colors
- Effective in any water temperature or washer type
- Gentle on fibers while removing deep stains
Cons
- Gel may feel sticky if over‑applied
- Small bottle requires frequent refills for heavy users
- Brush can wear out with extensive use
2. Shout Advanced Grease Busting Foam
Shout Advanced Grease‑Busting Foam is the go‑to solution for stubborn oil, motor‑oil, bike‑grease, and cooking‑oil stains that regular detergents can’t tackle.
Packaged in an 18 oz aerosol can, this foam sprays directly onto the blemish, where its three‑ingredient formula clings, penetrates, and lifts the grease away before the wash cycle even begins.
The foam is 50× more concentrated than in‑wash boosters, so a little goes a long way, and it works safely on both whites and colors in any water temperature, including HE and standard washers.
After a quick spray, let it sit, toss the garment in the machine, and watch the stain disappear—no pre‑soak, no extra steps. Whether you’re a DIY mechanic, a cyclist, or just a home chef, this foam keeps your clothes looking fresh without sacrificing fabric softness.
Pros
- Powerful three‑ingredient grease‑dissolving formula
- 50× concentrated, so a small amount suffices
- Works in any water temperature and washer type
- Safe on both whites and colored fabrics
- Quick spray‑apply, no extra pre‑soak needed
Cons
- Aerosol can may feel bulky for travel
- Strong scent can linger if over‑applied
- Requires ventilation during use for best comfort
1. Shout Active Enzyme Prewash Spray
Shout Active Enzyme Laundry Stain Remover Spray is a 22 oz pre‑wash powerhouse that tackles more than 100 everyday stains. The enzyme‑rich formula clings to the spot, penetrates fabric fibers, and lifts grime so it can be washed away later.
It’s 50× more concentrated than a typical in‑wash booster, so a light mist does the heavy lifting. The spray works on all machine‑washable whites and colors, in any water temperature, and is safe for both HE and standard washers.
After spraying, simply rub the area and let the treated garment sit up to a week before laundering. The bottle itself is greener too—its body (minus trigger and label) contains 25 % post‑consumer recycled plastic, making it a smarter choice for the planet.
Pros
- 50× more concentrated than regular boosters
- Works on whites, colors, and all water temps
- Handles food, wine, blood, grass, and more
- Eco‑friendly bottle with 25 % recycled plastic
- Quick spray‑rub‑wash routine saves time
Cons
- May need second spray for set‑in stains
- Fragrance can be strong for sensitive noses
- Not intended for dry‑clean‑only fabrics
Frequently Asked Questions
What’s the most effective household item for removing grease stains from clothing?
Dish soap (especially a concentrated, grease-fighting brand) works wonders. Apply a few drops directly to the stain, gently rub it in with your fingertips or a soft brush, let it sit for 5‑10 minutes, then launder as usual in the warmest water safe for the fabric.
Are there any natural alternatives if I prefer chemical‑free solutions?
Yes—baking soda and white vinegar are great natural options:
1. Sprinkle a generous amount of baking soda on the fresh grease spot and let it absorb for 10‑15 minutes.
2. Brush off the powder, then dab the area with a mixture of equal parts white vinegar and water.
3. Rinse, then wash the garment normally. The combination lifts the oil and neutralizes any lingering odor.
How can I prevent grease stains from setting in before I get to the laundry?
Act quickly with these steps:
– Blot, don’t rub: Use a clean paper towel or cloth to soak up excess grease.
– Apply a pre‑treatment: Spray or rub a small amount of liquid laundry detergent or a commercial stain remover onto the spot.
– Cold water rinse: Run cold water through the back of the stain to push the oil out of the fibers.
– Avoid heat: Do not tumble‑dry until you’re sure the stain is gone, as heat can permanently set the grease.
Conclusion
When tackling greasy spots, the most effective approach combines prompt action, the right cleaning method, and a bit of patience.
Acting quickly prevents the oil from setting, while pre‑treating with a suitable agent—whether a liquid detergent, a natural oil‑breaker, or a specialized stain remover—helps lift the residue before it bonds with fibers.
Gentle agitation and the appropriate water temperature further enhance removal without damaging the fabric.
Finally, always test any solution on an inconspicuous area and follow care‑label instructions, ensuring your clothes stay fresh, vibrant, and ready for the next wear.













Henry Kenner